Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation
نویسندگان
چکیده
منابع مشابه
Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation
This article reports an efficient CH activation process for regioselective halogenation of 1,4-benzodiazepinones. Direct halogenation with NXS (X = Br, I) affords halogenated benzodiazepinones on the central aromatic ring whereas catalyst (Pd(OAc)2) controlled CH activation furnishes regioselectively ortho halogenated benzodiazepinones on the phenyl side chain.
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep12131